“Why so many vaccinated people are getting sick: Antibody Dependent Enhancement (ADE)”; and “Exclusive Summary: Covid-19 Vaccine Concerns”

by SHARYL ATTKISSON from the following:
1) https://sharylattkisson.com/2021/08/study-why-so-many-vaccinated-people-are-getting-sick/ and
2) https://sharylattkisson.com/2021/08/exclusive-summary-covid-19-vaccine-concerns/

File:Antibody dependent enhancement.svg - Wikipedia

Why so many vaccinated people are getting sick: Antibody Dependent Enhancement (ADE)

According to studies:

  • ADE can make vaccinated people more susceptible to serious infection from the virus
  • “ADE may be a concern” for those who have been vaccinated for Covid-19
  • With ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in “increased viral replication and more severe disease, leading to major safety risks”
  • ADE can also “occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don’t protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness”
  • This concern was initially described by some scientists who were subsequently banned from media platforms that incorrectly claimed the scientists were disseminating disinformation
  • Study scientists suggest the answer is to create a new vaccine

In a new study in the Journal of Infection, scientists explain one likely reason why so many vaccinated people are getting sick: a dangerous phenomenon called Antibody Dependent Enhancement or ADE.

Despite the fact that multiple medical authorities predicted, told us, and hoped, ADE would not impact Covid-19 vaccines, data from the study indicates it has done just that.

According to the new study, data suggests that the Covid-19 vaccines originally appeared to provide an overall benefit in fighting the virus. However, when it comes to one of the newer iterations of Covid, the Delta variant, the vaccines appear to facilitate infection displaying “a strikingly increased affinity” for the virus’ trademark spike protein.

The scientists conclude that “ADE may be a concern” for those who have been vaccinated for Covid-19.

Read the study here.

According to scientific study, the ADE risk was well known prior to the Covid-19 vaccines being allowed on the market.

“One potential hurdle for antibody-based vaccines and therapeutics is the risk of exacerbating COVID-19 severity via antibody-dependent enhancement (ADE),” explained a study in Nature. “ADE can increase the severity of multiple viral infections, including other respiratory viruses such as respiratory syncytial virus (RSV) and measles.”

Scientists say that with ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in “increased viral replication and more severe disease, leading to major safety risks.”

“Non-neutralizing antibodies generated by past infection or vaccination fail to shut down the pathogen upon re-exposure. Instead, they act as a gateway by allowing the virus to gain entry and replicate in cells that are usually off limits… That, in turn, can lead to wider dissemination of illness, and over-reactive immune responses that cause more severe illness,” according to scientists.

An article in MedPage (prior to the new study) dismissed concerns about ADE, but noted it “can also occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don’t protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness.”

On the other hand, most scientific studies on this topic say those who have recovered from Covid-19 have natural immunity that does not display the same problem, and appears to be superior to that, so far, of that provided by the vaccines.

Nonetheless, the Centers for Disease Control (CDC) and many public health officials are pressing for more people to get vaccinated, including those who have been previously-infected with Covid. (Numerous studies suggest there is no benefit to recovered patients getting vaccinated.) The health officials state that the vaccinated patients who are getting Covid are getting milder forms than they would have if they had not been vaccinated. However, that is a case-by-case assumption and is impossible to prove.

In Israel, health officials say that only 1% among Covid infections in the latest wave are among those previously infected with Covid. The other 99% are among unvaccinated and not previously-infected, and among fully-vaccinated.

According to the new study, the solution to the current ADE problem is to invent a new, updated version of the vaccine.

Children’s Hospital of Philadelphia (which accepts funding from the vaccine industry) reports the following about ADE:

A major goal of antibodies is to bind to the pathogen and prevent it from infecting, or entering, a cell. Antibodies that prevent entry into cells are called neutralizing antibodies. Many vaccines work by inducing neutralizing antibodies. However, not all antibody responses are created equal. Sometimes antibodies do not prevent cell entry and, on rare occasions, they may actually increase the ability of a virus to enter cells and cause a worsening of disease through a mechanism called antibody-dependent enhancement (ADE).

What is ADE?

ADE occurs when the antibodies generated during an immune response recognize and bind to a pathogen, but they are unable to prevent infection. Instead, these antibodies act as a “Trojan horse,” allowing the pathogen to get into cells and exacerbate the immune response.

Is ADE caused by vaccines?

On a few occasions ADE has resulted from vaccination:

  • Respiratory syncytial virus (RSV) — RSV is a virus that commonly causes pneumonia in children. A vaccine was made by growing RSV, purifying it, and inactivating it with the chemical formaldehyde. In clinical trials, children who were given the vaccine were more likely to develop or die from pneumonia after infection with RSV. As a result of this finding, the vaccine trials stopped, and the vaccine was never submitted for approval or released to the public.
  • Measles — An early version of measles vaccine was made by inactivating measles virus using formaldehyde. Children who were vaccinated and later became infected with measles in the community developed high fevers, unusual rash, and an atypical form of pneumonia. Upon seeing these results, the vaccine was withdrawn from use, and those who received this version of the vaccine were recommended to be vaccinated again using the live, weakened measles vaccine, which does not cause ADE and is still in use today.

A more recent example of ADE following vaccination comes from dengue virus:

  • Dengue virus — In 2016, a dengue virus vaccine was designed to protect against all four serotypes of the virus. The hope was that by inducing immune responses to all four serotypes at once, the vaccine could circumvent the issues related to ADE following disease with dengue virus. The vaccine was given to 800,000 children in the Philippines. Fourteen vaccinated children died after encountering dengue virus in the community. It is hypothesized that the children developed antibody responses that were not capable of neutralizing the natural virus circulating in the community. As such, the vaccine was recommended only for children greater than 9 years of age who had already been exposed to the virus.

Should I be concerned that my child will develop ADE after receiving a vaccination?

Today’s routinely recommended vaccines do not cause ADE. If they did, like those described above, they would be removed from use. Phase III clinical trials are designed to uncover frequent or severe side effects before a vaccine is approved for use.

Read more on ADE here.

Read more from the new study below:

Antibody dependent enhancement (ADE) of infection is a safety concern for vaccine strategies. In a recent publication, Li et al. (Cell 184 :1-17, 2021) have reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo. However, this study was performed with the original Wuhan/D614G strain. Since the Covid-19 pandemic is now dominated with Delta variants, we analyzed the interaction of facilitating antibodies with the NTD of these variants. Using molecular modelling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs. We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain. However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors). Under these circumstances, second generation vaccines with spike protein formulations lacking structurally-conserved ADE-related epitopes should be considered.The aim of the present study was to evaluate the recognition of SARS-CoV-2 Delta variants by infection enhancing antibodies directed against the NTD. The antibody studied is 1054 (pdb file #7LAB) which has been isolated from a symptomatic Covid-19 patient1. Molecular modelling simulations were performed as previously described2. Two currently circulating Delta variants were investigated, with the following mutational patterns in the NTD :

  • – G142D/E154K (B.1.617.1)
  • – T19R/E156G/del157/del158/A222V (B.1.617.2)

Each mutational pattern was introduced in the original Wuhan/D614G strain, submitted to energy minimization, and then tested for antibody binding. The energy of interaction (ΔG) of the reference pdb file #7LAB (Wuhan/D614G strain) in the NTD region was estimated to -229 kJ/mol−1. In the case of Delta variants, the energy of interaction was raised to -272 kJ.mol−1(B.1.617.1) and -246 kJ.mol−1 (B.1.617.2). Thus, these infection enhancing antibodies not only still recognize Delta variants but even display a higher affinity for those variants than for the original SARS-CoV-2 strain.The global structure of the trimeric spike of the B.1.617.1 variant in the cell-facing view is shown in Figure 1A. As expected, the facilitating antibody bound to the NTD (in green) is located behind the contact surface so that it does not interfere with virus-cell attachment. Indeed, a preformed antibody-NTD complex could perfectly bind to the host cell membrane. The interaction between the NTD and a lipid raft is shown in Figure 1B, and a whole raft-spike-antibody complex in Figure 1C. Interestingly, a small part of the antibody was found to interact with the lipid raft, as further illustrated in Figures 1D-E. More precisely, two distinct loops of the heavy chain of the antibody encompassing amino acid residues 28-31 and 72-74, stabilize the complex through a direct interaction with the edge of lipid raft (Figure 1F). Overall, the energy of interaction of the NTD-raft complex was raised from -399 kJ.mol−1 in absence of the antibody to -457 kJ.mol−1 with the antibody. By clamping the NTD and the lipid raft, the antibody reinforces the attachment of the spike protein to the cell surface and thus facilitates the conformational change of the RBD which is the next step of the virus infection process2.

Figure 1
Figure 1Infection enhancing antibodies recognize the NTD of Delta variants. A. Molecular model of the Delta B.1.617.1 spike trimer as viewed from the host cell surface (chains A, B and C in cyan, yellow and purple, respectively), with the NTD and RBD of each chain indicated. The 1054 antibody is in green. B. Spike trimer with the B subunit bound to a lipid raft (with 6 ganglioside GM1 molecules). C. Trimolecular [spike-antibody-raft] complex. D. Focus on the NTD-antibody complex bound to the lipid raft. E. Secondary structures of the NTD (yellow) and the antibody (green) bound to lipid raft gangliosides. F. The 1054 antibody clamps the NTD and the edge of the lipid raft.

____________________________________________________

(UPDATED) Exclusive Summary: Covid-19 Vaccine Concerns

  • Updated Sept. 4, 2021 with acute CNS demyelination after Pfizer and Moderna vaccines
  • Updated Aug. 30, 2021 with Functional Neurological Disorder
  • Updated Aug. 24, 2021 with waning immunity
  • Updated Aug. 17, 2021 with Bell’s Palsy analysis, Hong Kong
  • Updated Aug. 16, 2021 with Antibody Dependent Enhancement (ADE) study
  • Updated Aug. 5, 2021 with heart disorders more common than CDC reported from database
  • Updated July 22, 2021 with EU warning about Guillain-Barre autoimmune paralysis after Johnson and Johnson vaccination.
  • Updated July 12, 2021 with new FDA warning of Guillain-Barre autoimmune paralysis cases after vaccination.
  • Updated July 12, 2021 with reports of Graves disease autoimmune disorder after vaccination.
  • Updated July 1, 2021 with reports of Guillain-Barre paralysis cases after vaccination.
  • Updated June 30, 2021 with news of first case of blood clot disorder in double-dose RNA vaccine.

If you find yourself confused about the mixed guidance when it comes to Covid-19 vaccines and safety concerns, you’re not alone.

While the Centers for Disease Control (CDC) is marketing widespread use of the emergency-use vaccines in the U.S. for both old and young alike, many other countries are limiting Covid-19 vaccine use. Health officials around the world are giving varying advice on safety issues as Covid-19 vaccines are given to more people, and more information can be collected.

Read CDC’s information here.

Below are summaries of some of the concerns that have emerged or been raised by medical officials.

Click here to jump to: Summary by safety concern

Click here to jump to: Summary by vaccine

Click here to jump to: Summary by country

Click here to jump to: Additional reading and studies

Summary by safety concern

General

In the UK, some scientists analyzed adverse event reports and called upon the Medicines and Healthcare Products Regulatory Agency to stop the Covid-19 vaccines as “not safe for human use” due to reports of issues with bleeding/clotting, pain, immune system, neurological, loss of sight/hearing/smell/speech, and questions about impact in pregnant women.

A petition of scientists led by Linda Wastila, Professor, Pharmaceutical Health Services Research University of Maryland School of Pharmacy is calling for Covid-19 vaccines to be disapproved.

Fifty-seven authors from 17 countries have signed an endorsement urging that Covid-19 vaccinations be stopped unless new safety mechanisms are immediately implemented.

The authors include Dr. Peter McCullough, cardiologist and former Vice Chief of Medicine at Baylor University Medical Center in Dallas, Texas, who has called for a halt to vaccinating 30-year olds due to “no clinical benefit” and safety concerns. [McCullough is currently Senior Professor of Internal Medicine at the Texas A&M University Health Sciences Center.]

Acute CNS Demyelination and Multiple Sclerosis

A new study in Journal of Neurology examines possible links between Pfizer and Moderna vaccines, and acute Central Nervous System (CNS) demyelination, including Multiple Sclerosis (MS).

Demyelinating diseases damage the protective covering surrounding nerve fibers in the brain, optic nerves and spinal cord, causing neurological problems. In the study, four patients had the Pfizer vaccine and three had the Moderna vaccine. Within 21 days of the first or second dose, the patients developed active CNS demyelination of the optic nerve, brain, and/or spinal cord leading to “visual loss, dysmetria, gait instability, paresthesias, sphincter disturbance, and limb weakness.”

Age ranged from 24 to 64 years old. Four patients were ultimately diagnoses with exacerbation of their stable MS.

Two were diagnosed with new cases of MS.

One was diagnosed with neuromyelitis optica.

Functional Neurological Disorder (FND)

Researchers in the United Kingdom are studying two additional cases of Functional Neurological Disorder (FND) in women in their 30s after receiving Covid-19 vaccines.

FND is a neurological disorder involving malfunctioning of the nervous system and how the brain and body transmit signals. Symptoms can include limb weakness, paralysis, tremor, spasms, problems walking, speech problems, tingling, vision loss, seizures, fatigue, anxiety, chronic pain, memory symptoms, and blackouts.

An analysis of Covid-19 vaccine adverse events showed hundreds of thousands of reports of such symptoms.

In January, videos showing vaccine patients suffering such symptoms were treated by media outlets such as Wired as if they were fake news and “dangerous” misinformation.

In fact, the videos garnered the attention of scientists who investigated and concluded they were early warnings of what happens to some who get Covid-19 vaccines.

The newest cases are outlined in the journal NeuroPsychiatry and include:

  • A 38-year old woman who got her first dose of Pfizer’s vaccine and quickly developed weakness around her ear, mouth, left arm and leg. She went to the ER the next day and was diagnosed with Bell’s palsy or a transient ischemic attack. Problems continued months later, including memory issues, and she was diagnosed with FND.
  • A 36-year-old woman who got her second dose of Moderna and quickly noticed weakness in right hand and right leg limping. A day later she reported severe leg heaviness, fatigue, movement difficulties. After physical therapy her right-side weakness improved but she awoke weeks later with left-side weakness, tightness and heaviness in neck, difficulties with daily living, rapid muscle fatigue, dragging right foot, and tremor. She was diagnosed with FND.

Antibody Dependent Enhancement (ADE)

Updated (read more here). According to studies:

  • Antibody Dependent Enhancement (ADE) can make vaccinated people more susceptible to serious infection from the virus
  • “ADE may be a concern” for those who have been vaccinated for Covid-19
  • With ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in “increased viral replication and more severe disease, leading to major safety risks”
  • ADE can also “occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don’t protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness”
  • This concern was initially described by some scientists who were subsequently banned from media platforms that incorrectly claimed the scientists were disseminating disinformation

Waning immunity

Update Aug. 24, 2021: With evidence of seriously-waning immunity at the five- to six-month mark, CDC is now recommending a third “booster” shot. In highly-vaccinated Israel, recognition that vaccination likely does not confer protection beyond a few months, the country has reimagined its vaccine passports. They will only apply to people who have had three shots, and only be good for a six month period of time.

Guillain-Barre syndrome autoimmune paralysis

Update July 22, 2021: The European Union added Guillain-Barré syndrome, an autoimmune paralysis disorder, as a possible side effect from Johnson and Johnson’s Covid-19 vaccine. 

Update July 12, 2021: The FDA added warnings about Guillain-Barre autoimmune paralysis, in which the immune system attacks the body’s nerves, after Johnson and Johnson vaccine. According to reports, the cases have primarily been reported about two weeks after vaccination, mostly in men, and “any aged 50 and older.”

Numerous case reports of Guillain-Barre syndrome paralysis after Covid-19 vaccine have prompted scientists to warn that “all physicians” should be “vigilant in recognizing Guillain-Barré syndrome in patients who have received the AstraZeneca vaccine… our observations suggest that this clinically distinct [Guillain-Barré syndrome] variant is more severe than usual and may require mechanical ventilation.” In the U.K., scientists flagged “bifacial weakness and normal facial sensation in four men between 11 and 22 days after their first doses of the Astra-Zeneca vaccine.” A case has also been reported in a patient who got the Pfizer vaccine. In India, there are reports of seven severe cases of Guillain-Barré syndrome 10 to 14 days after the first dose of AstraZeneca’s vaccine. Six were women, all had facial paralysis, “all progressed to quadriplegia, and six required respiratory support. Patients’ ages ranged from 43 to 70. Four developed other cranial neuropathies, including abducens palsy and trigeminal sensory nerve involvement.”

Guillain-Barre syndrome has been reported after other vaccinations. The cause is believed to be damage to the immune system. The disorder can be extremely serious and can lead to total paralysis with dependence on artificial respiration. Even those who recover may have serious muscle wasting and may have to slowly teach the body to relearn most every normal task, such as walking. One in 20 cases is fatal.

Bell’s Palsy

Updated Aug. 17: An analysis in Hong Kong shows risk of Bell’s palsy is higher with CoronaVac (Sinovac Biotech) shot, a vaccine formulation not currently used in U.S. Bell’s palsy is facial paralysis, muscle twitching, or weakness. It may include change in taste, and pain around the ear, increased sensitivity to sound known as hyperacusis. An adverse event analysis of U.S. reports shows 4,154 Bell’s Palsy after Covid-19 vaccination.

Heart issues

The Food and Drug Administration has added a new warning to Pfizer and Moderna Covid-19 vaccines about risk of heart inflammation.

As of June of 2021, CDC said that more than 1,200 cases of heart inflammation (myocarditis or pericarditis) in young people had been reported after Pfizer and Moderna Covid-19 vaccination.

  • More than half were after the second dose.
  • Most of the injuries are in males under age 30.

Updated Aug. 4: A new, independent study of medical records found the incidences of myocarditis and pericarditis are more than five times more common than CDC reported.

The Israeli Ministry of Health announced it’s monitoring for heart inflammation after Pfizer’s vaccine due to reports of problems.

Myocarditis and Other Cardiovascular Complications of the mRNA-Based COVID-19 Vaccines [Pfizer-BioNTech, Moderna] in a number of patients are described in a scientific article:

  • Two patients with clinically suspected myocarditis
  • One patient with stress cardiomyopathy 
  • Two patients with pericarditis 

According to the research: 

  • The two patients with clinically suspected myocarditis were otherwise healthy young men who presented with acute substernal chest pressure and/or dyspnea after receiving the second dose of the vaccine and were found to have diffuse ST elevations on electrocardiogram (ECG), elevated cardiac biomarkers and inflammatory markers, and mildly reduced left ventricular (LV) function on echocardiography. Both patients met the modified Lake Louise Criteria for acute myocarditis by cardiac magnetic resonance imaging. 
  • A case of stress cardiomyopathy occurred in a 60-year-old woman with known coronary artery disease (CAD) and previously normal LV function, who presented with new exertional symptoms, ECG changes, and apical akinesis following the second dose of the vaccine. 
  • The two patients with pericarditis who presented with chest pain, elevated inflammatory markers, and pericardial effusions after receiving the vaccine.

Blood clots

In late June, the first case of a blood clot disorder called “thrombosis with thrombocytopenia” after an RNA double-dose vaccine was been reported in the Annals of Internal Medicine. The case was that of a 65-year-old man who developed symptoms ten days after his second dose of the Moderna vaccine. Because the blood clot disorder was not previously warned about in the Moderna and Pfizer vaccines, doctors treated the patient with heparin, the very drug that’s not supposed to be used in post-vaccine patients suffering from the disorder because it could actually worsen the condition.

The Johnson and Johnson Covid-19 vaccine was temporarily removed from the market in the U.S. on April 16, 2021 while health officials studied reports of blood clot injuries. Among them was an 18-year old teen named Emma Burkey, who got sick about a week after the Johnson and Johnson Covid-19 vaccine and ended up having three brain surgeries related to blood clots and seizures.

Read: BBC radio news anchor dies of blood clots after Covid vaccine

The Johnson and Johnson vaccine was allowed back on the market April 27, 2021 with new warnings about the disorder.

Swedish health officials determined that people under age 65 should not get the Johnson and Johnson vaccine due to reports of blood clots.

An editorial published in the Journal of the American Medical Association recommended women under age 50 avoid the Johnson and Johnson Covid-19 vaccine due to concerns about blood clots. The recommendation discussed 12 case reports of a blood disorder known as cerebral venous sinus thrombosis (CVST) with thrombocytopenia following the Johnson and Johnson vaccine.

The AstraZeneca Covid-19 vaccine (not currently approved in the U.S.) has been linked to a dangerous disorder involving blood clots with low blood platelets. On April 7, 2021, the European Medicines Agency says it made the association after it analyzed 62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic vein thrombosis reported in the EU drug safety database (EudraVigilance) as of March 22, 2021; 18 of which were fatal.

An otherwise healthy South Florida doctor, Gregory Michael, died of a brain hemorrhage 16 days after he got Pfizer’s Covid-19 vaccine. Authorities concluded he died of a blood disorder called “immune thrombocytopenia” (ITP) that can prevent blood from clotting and cause internal bleeding. His wife said a blood test showed the level of his platelets to be at “zero.” She said before the shot, Dr. Michael had “absolutely no medical issues” and no underlying conditions. However, authorities later categorized his death as “natural.”

In Spain, the AstraZeneca shot has been restricted in people under age 60 due to reports of blood clots in younger people.

Bulgaria, Iceland and Norway have halted AstraZeneca shots. 

Austria, Italy and Romania banned certain “lots” or batches of the AstraZeneca shots.

Denmark stopped using the AstraZeneca Covid-19 vaccine altogether as well as the Johnson and Johnson vaccine after investigations into blood clots, saying “the benefits of using the COVID-19 vaccine from Johnson & Johnson do not outweigh the risk of causing the possible adverse effect in those who receive the vaccine.”

The Italian government recently restricted AstraZeneca Covid-19 vaccine to adults over age 60 after a teenager who got the shot died from a rare form of blood clotting. Eighteen-year-old Camilla Canepa died after getting vaccinated May 25, 2021. 

Several other European countries have also stopped giving the AstraZeneca Covid-19 vaccine to people below a certain age, usually ranging from 50 to 65. 

Graves disease autoimmune disorder

Studies in Mexico and Turkey link the autoimmune thyroid disorder Graves disease to Covid-19 vaccination in numerous female health care workers, including two who were breastfeeding. Pfizer-BioNTech was the vaccine given in Mexico. A Chinese vaccine was given in Turkey. Read more at the link below.

https://sharylattkisson.com/2021/07/two-studies-covid-19-vaccines-trigger-graves-disease-in-some-female-health-care-workers/

Frail, elderly

Health officials in Norway sounded the alarm after 23 patients died shortly after getting the Pfizer Covid-19 vaccine. They advise doctors to use caution in administering the shot to “very frail elderly patients.” 

After investigating 13 of the deaths, the Norwegian authorities concluded that common side effects from so-called “RNA” vaccines may be too much for a frail elderly person to handle, and may contribute to their death. 

“There is a possibility that these common adverse reactions, that are not dangerous in fitter, younger patients and are not unusual with vaccines, may aggravate underlying disease in the elderly,” said Steinar Madsen, medical director of the Norwegian Medicines Agency.

CDC said it is monitoring the impact of the vaccines on already-frail patients such as the chronically ill in nursing homes.

Several clusters of elderly patients in U.S. nursing homes died after Pfizer or Moderna Covid-19 vaccine. In one group, a number of the patients who died tested positive for Covid-19 after vaccination.

Pregnant women

Several Brazilian states suspended use of AstraZeneca’s Covid-19 vaccine for pregnant women in May 2021 after a pregnant woman died after getting vaccinated. The decisions follow the recommendation of the country’s National Health Surveillance Agency, which recommended “immediate suspension” of the AstraZeneca Covid-19 vaccine for pregnant women after results of vaccine adverse events monitoring in the country.

CDC says that with limited data on impact of Covid-19 vaccine in pregnant women and on their unborn children, the decision on whether to vaccinate while pregnant is an individual decision to be made between a woman and her physician.

Previously-infected

CDC falsely claimed that studies showed Covid-19 vaccines are effective for those who already had Covid-19. In fact, studies showed the opposite.

Manufacturing problems

On June 11, the European Union’s drug regulator announced it will not use batches of the Johnson & Johnson COVID-19 vaccine that were made at a Baltimore, Maryland-based plant around the time that cross-contamination manufacturing problems were reported at the facility.

Anonymous sources claimed that up to 60 million doses of the Johnson and Johnson vaccine had to be thrown out. But the FDA issued a news release saying that two batches from the Baltimore plant were safe to use. The FDA said “several other batches are not suitable for use, but additional batches are still under review.”

Lack of immunity

Israel announced that about half of the adults infected with Covid-19 during its outbreak in the June 2021 time period were fully vaccinated. The fully-vaccinated individuals had gotten Pfizer’s shots.

According to Epoch Times, in June 2021 nearly 4,000 fully vaccinated people in Massachusetts tested positive for Covid-19. On April 30, “the CDC reported that some 10,626 breakthrough cases were reported in 46 states and territories.” Breakthrough cases are where fully vaccinated people still end up infected with Covid-19.

Scientists hoped that Covid-19 vaccines would be effective in variants of Covid-19, which are mutations that occur naturally with viruses and were always expected with Covid-19. However, the vaccine effectiveness against variants may be limited. CDC and vaccine makers are studying the medical landscape to find out more.

Other states, such as Maine, are noting Covid-19 deaths occurring in fully vaccinated people.

Summary by vaccine

Pfizer and Moderna

Acute CNS Demyelination and Multiple Sclerosis

A new study in Journal of Neurology examines possible links between Pfizer and Moderna vaccines, and acute Central Nervous System (CNS) demyelination, including Multiple Sclerosis (MS).

Demyelinating diseases damage the protective covering surrounding nerve fibers in the brain, optic nerves and spinal cord, causing neurological problems. In the study, four patients had the Pfizer vaccine and three had the Moderna vaccine. Within 21 days of the first or second dose, the patients developed active CNS demyelination of the optic nerve, brain, and/or spinal cord leading to “visual loss, dysmetria, gait instability, paresthesias, sphincter disturbance, and limb weakness.”

Age ranged from 24 to 64 years old. Four patients were ultimately diagnoses with exacerbation of their stable MS.

Two were diagnosed with new cases of MS.

One was diagnosed with neuromyelitis optica.

Waning Immunity

Update Aug. 24, 2021: With evidence of seriously-waning immunity at the five- to six-month mark, CDC is now recommending a third “booster” shot. In highly-vaccinated Israel, recognition that vaccination likely does not confer protection beyond a few months, the country has reimagined its vaccine passports. They will only apply to people who have had three shots, and only be good for a six month period of time.

Functional Neurological Disorder (FND)

Updated Aug. 30, 2021: Researchers in the United Kingdom are studying two additional cases of Functional Neurological Disorder (FND) in women in their 30s after receiving Covid-19 vaccines.

FND is a neurological disorder involving malfunctioning of the nervous system and how the brain and body transmit signals. Symptoms can include limb weakness, paralysis, tremor, spasms, problems walking, speech problems, tingling, vision loss, seizures, fatigue, anxiety, chronic pain, memory symptoms, and blackouts.

An analysis of Covid-19 vaccine adverse events showed hundreds of thousands of reports of such symptoms.

In January, videos showing vaccine patients suffering such symptoms were treated by media outlets such as Wired as if they were fake news and “dangerous” misinformation.

In fact, the videos garnered the attention of scientists who investigated and concluded they were early warnings of what happens to some who get Covid-19 vaccines.

The newest cases are outlined in the journal Neurology and include:

  • A 38-year old woman who got her first dose of Pfizer’s vaccine and quickly developed weakness around her ear, mouth, left arm and leg. She went to the ER the next day and was diagnosed with Bell’s palsy or a transient ischemic attack. Problems continued months later, including memory issues, and she was diagnosed with FND.
  • A 36-year-old woman who got her second dose of Moderna and quickly noticed weakness in right hand and right leg limping. A day later she reported severe leg heaviness, fatigue, movement difficulties. After physical therapy her right-side weakness improved but she awoke weeks later with left-side weakness, tightness and heaviness in neck, difficulties with daily living, rapid muscle fatigue, dragging right foot, and tremor. She was diagnosed with FND.

Antibody Dependent Enhancement (ADE)

Updated (read more here). According to studies:

  • Antibody Dependent Enhancement (ADE) can make vaccinated people more susceptible to serious infection from the virus
  • “ADE may be a concern” for those who have been vaccinated for Covid-19
  • With ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in “increased viral replication and more severe disease, leading to major safety risks”
  • ADE can also “occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don’t protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness”
  • This concern was initially described by some scientists who were subsequently banned from media platforms that incorrectly claimed the scientists were disseminating disinformation

Numerous case reports of Guillain-Barre syndrome paralysis after Covid-19 vaccine have prompted scientists to warn that “all physicians” should be “vigilant in recognizing Guillain-Barré syndrome in patients who have received the AstraZeneca vaccine… our observations suggest that this clinically distinct [Guillain-Barré syndrome] variant is more severe than usual and may require mechanical ventilation.” In the U.K., scientists flagged “bifacial weakness and normal facial sensation in four men between 11 and 22 days after their first doses of the Astra-Zeneca vaccine.” A case has also been reported in a patient who got the Pfizer vaccine. In India, there are reports of seven severe cases of Guillain-Barré syndrome 10 to 14 days after the first dose of AstraZeneca’s vaccine. Six were women, all had facial paralysis, “all progressed to quadriplegia, and six required respiratory support. Patients’ ages ranged from 43 to 70. Four developed other cranial neuropathies, including abducens palsy and trigeminal sensory nerve involvement.”

Guillain-Barre syndrome has been reported after other vaccinations. The cause is believed to be damage to the immune system. The disorder can be extremely serious and can lead to total paralysis with dependence on artificial respiration. Even those who recover may have serious muscle wasting and may have to slowly teach the body to relearn most every normal task, such as walking. One in 20 cases is fatal.

In late June, the first case of a blood clot disorder called “thrombosis with thrombocytopenia” after an RNA double-dose vaccine was been reported in the Annals of Internal Medicine. The case was that of a 65-year-old man who developed symptoms ten days after his second dose of the Moderna vaccine. Because the blood clot disorder was not previously warned about in the Moderna and Pfizer vaccines, doctors treated the patient with heparin, the very drug that’s not supposed to be used in post-vaccine patients suffering from the disorder because it could actually worsen the condition.

The Food and Drug Administration has added a new warning to Pfizer and Moderna Covid-19 vaccines about risk of heart inflammation.

As of June of 2021, CDC said that more than 1,200 cases of heart inflammation (myocarditis of pericarditis) in young people had been reported after Pfizer and Moderna Covid-19 vaccination.

  • More than half were after the second dose.
  • Most of the injuries are in males under age 30.

Updated Aug. 4: A new, independent study of medical records found the incidences of myocarditis and pericarditis are more than five times more common than CDC reported.

The Israeli Ministry of Health announced it’s monitoring for heart inflammation after Pfizer’s vaccine due to reports of problems.

Myocarditis and Other Cardiovascular Complications of the mRNA-Based COVID-19 Vaccines [Pfizer-BioNTech, Moderna] in a number of patients are described in a scientific article:

  • Two patients with clinically suspected myocarditis
  • One patient with stress cardiomyopathy 
  • Two patients with pericarditis 

According to the research: 

  • The two patients with clinically suspected myocarditis were otherwise healthy young men who presented with acute substernal chest pressure and/or dyspnea after receiving the second dose of the vaccine and were found to have diffuse ST elevations on electrocardiogram (ECG), elevated cardiac biomarkers and inflammatory markers, and mildly reduced left ventricular (LV) function on echocardiography. Both patients met the modified Lake Louise Criteria for acute myocarditis by cardiac magnetic resonance imaging. 
  • A case of stress cardiomyopathy occurred in a 60-year-old woman with known coronary artery disease (CAD) and previously normal LV function, who presented with new exertional symptoms, ECG changes, and apical akinesis following the second dose of the vaccine. 
  • The two patients with pericarditis who presented with chest pain, elevated inflammatory markers, and pericardial effusions after receiving the vaccine.

An otherwise healthy South Florida doctor, Gregory Michael, died of a brain hemorrhage 16 days after he got Pfizer’s Covid-19 vaccine. Authorities concluded he died of a blood disorder called “immune thrombocytopenia” (ITP) that can prevent blood from clotting and cause internal bleeding. His wife said a blood test showed the level of his platelets to be at “zero.” She said before the shot, Dr. Michael had “absolutely no medical issues” and no underlying conditions. However, authorities later categorized his death as “natural.”

Health officials in Norway sounded the alarm after 23 patients died shortly after receiving the Pfizer Covid-19 vaccine. They advise doctors to use caution in administering the shot to “very frail elderly patients.” 

After investigating 13 of the deaths, the Norwegian authorities concluded that common side effects from so-called “RNA” vaccines may be too much for a frail elderly person to handle, and may contribute to their death. 

“There is a possibility that these common adverse reactions, that are not dangerous in fitter, younger patients and are not unusual with vaccines, may aggravate underlying disease in the elderly,” said Steinar Madsen, medical director of the Norwegian Medicines Agency.

CDC said it is monitoring the impact of the vaccines on already-frail patients such as the chronically ill in nursing homes.

Several clusters of elderly patients in U.S. nursing homes died after Pfizer or Moderna Covid-19 vaccine. In one group, a number of the patients who died tested positive for Covid-19 after vaccination.

Israel announced that about half of the adults infected with Covid-19 during its outbreak in the June 2021 time period were fully vaccinated. The fully-vaccinated individuals had gotten Pfizer’s shots.

Studies in Mexico and Turkey link the autoimmune thyroid disorder Graves disease to Covid-19 vaccination in numerous female health care workers, including two who were breastfeeding. Pfizer-BioNTech was the vaccine given in Mexico. A Chinese vaccine was given in Turkey. Read more at the link here.

Johnson and Johnson

Update July 22, 2021: The European Union added Guillain-Barré syndrome, an autoimmune paralysis disorder, as a possible side effect from Johnson and Johnson’s Covid-19 vaccine. 

Update July 12, 2021: The FDA added warnings about Guillain-Barre autoimmune paralysis, in which the immune system attacks the body’s nerves, after Johnson and Johnson vaccine. According to reports, the cases have primarily been reported about two weeks after vaccination, mostly in men, and “any aged 50 and older.”

The Johnson and Johnson Covid-19 vaccine was temporarily removed from the market in the U.S. on April 16, 2021 while health officials studied reports of blood clot injuries. 

Updated Aug. 4: A new, independent study of medical records found the incidences of myocarditis and pericarditis are more than five times more common than CDC reported.

The Johnson and Johnson vaccine was allowed back on the market April 27, 2021 with new warnings about the disorder.

Swedish health officials determined that people under age 65 should not get the Johnson and Johnson vaccine due to reports of blood clots.

An editorial in the Journal of the American Medical Association recommended women under age 50 avoid the Johnson and Johnson Covid-19 vaccine due to concerns about blood clots: a blood disorder known as cerebral venous sinus thrombosis (CVST) with thrombocytopenia following the Johnson and Johnson vaccine.

On June 11, the European Union’s drug regulator announced it will not use batches of the Johnson & Johnson COVID-19 vaccine that were made at a Baltimore, Maryland-based plant around the time that cross-contamination manufacturing problems were reported at the facility.

Anonymous sources claimed that up to 60 million doses of the Johnson and Johnson vaccine had to be thrown out. But the FDA issued a news release saying that two batches from the Baltimore plant were safe to use. The FDA said “several other batches are not suitable for use, but additional batches are still under review.”

Denmark  banned the Johnson and Johnson vaccine altogether saying “the benefits of using the COVID-19 vaccine from Johnson & Johnson do not outweigh the risk of causing the possible adverse effect in those who receive the vaccine”.

AstraZeneca (not given in the U.S.)

The AstraZeneca Covid-19 vaccine has been linked to a dangerous disorder involving blood clots with low blood platelets. 

On April 7, 2021, the European Medicines Agency says it made the association after it analyzed 62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic vein thrombosis reported in the EU drug safety database (EudraVigilance) as of March 22, 2021, 18 of which were fatal.

In Spain, the AstraZeneca shot has been restricted in people under age 60 due to reports of blood clots in younger people.

Bulgaria, Iceland and Norway have halted AstraZeneca shots. 

Austria, Italy and Romania banned certain “lots” or batches of the AstraZeneca shots.

Denmark stopped using the AstraZeneca Covid-19 vaccine altogether after investigations into blood clots.

The Italian government recently restricted AstraZeneca Covid-19 vaccine to adults over age 60 after a teenager who got the shot died from a rare form of blood clotting. Eighteen-year-old Camilla Canepa died after getting vaccinated May 25, 2021. 

Several other European countries have also stopped giving the AstraZeneca COVID-19 vaccine to people below a certain age, usually ranging from 50 to 65. 

Several Brazilian states suspended use of AstraZeneca’s Covid-19 vaccine for pregnant women in May 2021 after a pregnant woman died after getting vaccinated. The decisions follow the recommendation of the country’s National Health Surveillance Agency, which recommended “immediate suspension” of the AstraZeneca Covid-19 vaccine for pregnant women after results of vaccine adverse events monitoring in the country.

Numerous case reports of Guillain-Barre syndrome paralysis after Covid-19 vaccine have prompted scientists to warn that “all physicians” should be “vigilant in recognizing Guillain-Barré syndrome in patients who have received the AstraZeneca vaccine… our observations suggest that this clinically distinct [Guillain-Barré syndrome] variant is more severe than usual and may require mechanical ventilation.” In the U.K., scientists flagged “bifacial weakness and normal facial sensation in four men between 11 and 22 days after their first doses of the Astra-Zeneca vaccine.” A case has also been reported in a patient who got the Pfizer vaccine. In India, there are reports of seven severe cases of Guillain-Barré syndrome 10 to 14 days after the first dose of AstraZeneca’s vaccine. Six were women, all had facial paralysis, “all progressed to quadriplegia, and six required respiratory support. Patients’ ages ranged from 43 to 70. Four developed other cranial neuropathies, including abducens palsy and trigeminal sensory nerve involvement.”

Guillain-Barre syndrome has been reported after other vaccinations. The cause is believed to be damage to the immune system. The disorder can be extremely serious and can lead to total paralysis with dependence on artificial respiration. Even those who recover may have serious muscle wasting and may have to slowly teach the body to relearn most every normal task, such as walking. One in 20 cases is fatal.

Summary by country

Austria: Banned certain “lots” or batches of AstraZeneca shots.

Brazil: Several Brazilian states suspended use of AstraZeneca’s Covid-19 vaccine for pregnant women in May 2021 after a pregnant woman died after getting vaccinated. The decisions follow the recommendation of the country’s National Health Surveillance Agency, which recommended “immediate suspension” of the AstraZeneca Covid-19 vaccine for pregnant women after results of vaccine adverse events monitoring in the country.

Bulgaria: Halted AstraZeneca shots. 

Denmark: stopped using the AstraZeneca Covid-19 vaccine and the Johnson and Johnson vaccine altogether after investigations into blood clots.

European Union: July 22, 2021: The European Union added Guillain-Barré syndrome, an autoimmune paralysis disorder, as a possible side effect from Johnson and Johnson’s Covid-19 vaccine. 

The AstraZeneca Covid-19 vaccine (not currently approved in the U.S.) has been linked to a dangerous disorder involving blood clots with low blood platelets. On April 7, 2021, the European Medicines Agency says it made the association after it analyzed 62 cases of cerebral venous sinus thrombosis and 24 cases of splanchnic vein thrombosis reported in the EU drug safety database (EudraVigilance) as of March 22, 2021, 18 of which were fatal.

On June 11, the European Union’s drug regulator announced it will not use batches of the Johnson & Johnson COVID-19 vaccine that were made at a Baltimore, Maryland-based plant around the time that cross-contamination manufacturing problems were reported at the facility.

Several European countries have stopped giving the AstraZeneca COVID-19 vaccine to people below a certain age, usually ranging from 50 to 65. 

Numerous case reports of Guillain-Barre syndrome paralysis after Covid-19 vaccine have prompted scientists to warn that “all physicians” should be “vigilant in recognizing Guillain-Barré syndrome in patients who have received the AstraZeneca vaccine… our observations suggest that this clinically distinct [Guillain-Barré syndrome] variant is more severe than usual and may require mechanical ventilation.” In the U.K., scientists flagged “bifacial weakness and normal facial sensation in four men between 11 and 22 days after their first doses of the Astra-Zeneca vaccine.” A case has also been reported in a patient who got the Pfizer vaccine. In India, there are reports of seven severe cases of Guillain-Barré syndrome 10 to 14 days after the first dose of AstraZeneca’s vaccine. Six were women, all had facial paralysis, “all progressed to quadriplegia, and six required respiratory support. Patients’ ages ranged from 43 to 70. Four developed other cranial neuropathies, including abducens palsy and trigeminal sensory nerve involvement.”

Guillain-Barre syndrome has been reported after other vaccinations. The cause is believed to be damage to the immune system. The disorder can be extremely serious and can lead to total paralysis with dependence on artificial respiration. Even those who recover may have serious muscle wasting and may have to slowly teach the body to relearn most every normal task, such as walking. One in 20 cases is fatal.

Hong-Kong: Updated Aug. 17: An analysis in Hong Kong shows risk of Bell’s palsy is higher with CoronaVac (Sinovac Biotech) shot, a vaccine formulation not currently used in U.S. Bell’s palsy is facial paralysis, muscle twitching, or weakness. It may include change in taste, and pain around the ear, increased sensitivity to sound known as hyperacusis. An adverse event analysis of U.S. reports shows 4,154 Bell’s Palsy after Covid-19 vaccination.

Iceland: Has halted AstraZeneca shots. 

India: Numerous case reports of Guillain-Barre syndrome paralysis after Covid-19 vaccine have prompted scientists to warn that “all physicians” should be “vigilant in recognizing Guillain-Barré syndrome in patients who have received the AstraZeneca vaccine… our observations suggest that this clinically distinct [Guillain-Barré syndrome] variant is more severe than usual and may require mechanical ventilation.” In the U.K., scientists flagged “bifacial weakness and normal facial sensation in four men between 11 and 22 days after their first doses of the Astra-Zeneca vaccine.” A case has also been reported in a patient who got the Pfizer vaccine. In India, there are reports of seven severe cases of Guillain-Barré syndrome 10 to 14 days after the first dose of AstraZeneca’s vaccine. Six were women, all had facial paralysis, “all progressed to quadriplegia, and six required respiratory support. Patients’ ages ranged from 43 to 70. Four developed other cranial neuropathies, including abducens palsy and trigeminal sensory nerve involvement.”

Guillain-Barre syndrome has been reported after other vaccinations. The cause is believed to be damage to the immune system. The disorder can be extremely serious and can lead to total paralysis with dependence on artificial respiration. Even those who recover may have serious muscle wasting and may have to slowly teach the body to relearn most every normal task, such as walking. One in 20 cases is fatal.

Israel: The Israeli Ministry of Health announced it’s monitoring for heart inflammation after Pfizer’s vaccine due to reports of problems.

Announced that about half of the adults infected with Covid-19 during its outbreak in the June 2021 time period were fully vaccinated. The fully-vaccinated individuals had gotten Pfizer’s shots.

Update Aug. 24, 2021: In highly-vaccinated Israel, recognition that vaccination likely does not confer protection beyond a few months, the country has reimagined its vaccine passports. They will only apply to people who have had three shots, and only be good for a six month period of time.

ItalyRestricted AstraZeneca Covid-19 vaccine to adults over age 60 after a teenager who got the shot died from a rare form of blood clotting. Eighteen-year-old Camilla Canepa died after getting vaccinated May 25, 2021. 

Banned certain “lots” or batches of the AstraZeneca shots.

Mexico: Studies in Mexico and Turkey link the autoimmune thyroid disorder Graves disease to Covid-19 vaccination in numerous female health care workers, including two who were breastfeeding. Pfizer-BioNTech was the vaccine given in Mexico. A Chinese vaccine was given in Turkey. Read more at the link here.

Norway: Halted AstraZeneca shots. Cautioned use of the vaccine in “very frail elderly patients” after nearly two dozen deaths. 

“There is a possibility that these common adverse reactions, that are not dangerous in fitter, younger patients and are not unusual with vaccines, may aggravate underlying disease in the elderly,” said Steinar Madsen, medical director of the Norwegian Medicines Agency.

Romania: Banned certain “lots” or batches of the AstraZeneca shots.

Spain: The AstraZeneca shot has been restricted in people under age 60 due to reports of blood clots in younger people.

Sweden: Health officials determined that people under age 65 should not get the Johnson and Johnson vaccine due to reports of blood clots.

Turkey: Studies in Mexico and Turkey link the autoimmune thyroid disorder Graves disease to Covid-19 vaccination in numerous female health care workers, including two who were breastfeeding. Pfizer-BioNTech was the vaccine given in Mexico. A Chinese vaccine was given in Turkey. Read more at the link here.

UK: Some scientists analyzed adverse event reports and called upon the Medicines and Healthcare products Regulatory Agency to stop the Covid-19 vaccines as “not safe for human use” due to reports of issues with bleeding/clotting, pain, immune system, neurological, loss of sight/hearing/smell speech, and questions about impact in pregnant women.

Updated: Researchers in the United Kingdom are studying two additional cases of Functional Neurological Disorder (FND) in women in their 30s after receiving Covid-19 vaccines.

FND is a neurological disorder involving malfunctioning of the nervous system and how the brain and body transmit signals. Symptoms can include limb weakness, paralysis, tremor, spasms, problems walking, speech problems, tingling, vision loss, seizures, fatigue, anxiety, chronic pain, memory symptoms, and blackouts.

An analysis of Covid-19 vaccine adverse events showed hundreds of thousands of reports of such symptoms.

In January, videos showing vaccine patients suffering such symptoms were treated by media outlets such as Wired as if they were fake news and “dangerous” misinformation.

In fact, the videos garnered the attention of scientists who investigated and concluded they were early warnings of what happens to some who get Covid-19 vaccines.

The newest cases are outlined in the journal Neurology and include:

  • A 38-year old woman who got her first dose of Pfizer’s vaccine and quickly developed weakness around her ear, mouth, left arm and leg. She went to the ER the next day and was diagnosed with Bell’s palsy or a transient ischemic attack. Problems continued months later, including memory issues, and she was diagnosed with FND.
  • A 36-year-old woman who got her second dose of Moderna and quickly noticed weakness in right hand and right leg limping. A day later she reported severe leg heaviness, fatigue, movement difficulties. After physical therapy her right-side weakness improved but she awoke weeks later with left-side weakness, tightness and heaviness in neck, difficulties with daily living, rapid muscle fatigue, dragging right foot, and tremor. She was diagnosed with FND.

US: Update Sept. 4, 2021: Acute CNS Demyelination and Multiple Sclerosis

A new study in Journal of Neurology examines possible links between Pfizer and Moderna vaccines, and acute Central Nervous System (CNS) demyelination, including Multiple Sclerosis (MS).

Demyelinating diseases damage the protective covering surrounding nerve fibers in the brain, optic nerves and spinal cord, causing neurological problems. In the study, four patients had the Pfizer vaccine and three had the Moderna vaccine. Within 21 days of the first or second dose, the patients developed active CNS demyelination of the optic nerve, brain, and/or spinal cord leading to “visual loss, dysmetria, gait instability, paresthesias, sphincter disturbance, and limb weakness.”

Age ranged from 24 to 64 years old. Four patients were ultimately diagnoses with exacerbation of their stable MS.

Two were diagnosed with new cases of MS.

One was diagnosed with neuromyelitis optica.

Update Aug. 24, 2021: With evidence of seriously-waning immunity at the five- to six-month mark, CDC is now recommending a third “booster” shot. In highly-vaccinated Israel, recognition that vaccination likely does not confer protection beyond a few months, the country has reimagined its vaccine passports. They will only apply to people who have had three shots, and only be good for a six month period of time.

Update Aug. 16, 2021: Antibody Dependent Enhancement (ADE) (read more here). According to studies:

  • Antibody Dependent Enhancement (ADE) can make vaccinated people more susceptible to serious infection from the virus
  • “ADE may be a concern” for those who have been vaccinated for Covid-19
  • With ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in “increased viral replication and more severe disease, leading to major safety risks”
  • ADE can also “occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don’t protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness”
  • This concern was initially described by some scientists who were subsequently banned from media platforms that incorrectly claimed the scientists were disseminating disinformation

Update Aug. 4, 2021: A new, independent study of medical records found the incidences of myocarditis and pericarditis are more than five times more common than CDC reported.

Update July 12, 2021: The FDA added warnings about Guillain-Barre autoimmune paralysis, in which the immune system attacks the body’s nerves, after Johnson and Johnson vaccine. According to reports, the cases have primarily been reported about two weeks after vaccination, mostly in men, and “any aged 50 and older.”

In late June, the first case of a blood clot disorder called “thrombosis with thrombocytopenia” after an RNA double-dose vaccine was been reported in the Annals of Internal Medicine. The case was that of a 65-year-old man who developed symptoms ten days after his second dose of the Moderna vaccine. Because the blood clot disorder was not previously warned about in the Moderna and Pfizer vaccines, doctors treated the patient with heparin, the very drug that’s not supposed to be used in post-vaccine patients suffering from the disorder because it could actually worsen the condition.

Dr. Peter McCullough, cardiologist and Vice Chief of Medicine at Baylor University Medical Center in Dallas, Texas, has called for a halt to vaccinating 30-year olds due to “no clinical benefit” and safety concerns.

A petition of scientists led by Linda Wastila, Professor, Pharmaceutical Health Services Research University of Maryland School of Pharmacy is calling for Covid-19 vaccines to be disapproved.

The Food and Drug Administration has added a new warning to Pfizer and Moderna Covid-19 vaccines about risk of heart inflammation.

As of June of 2021, CDC said that more than 1,200 cases of heart inflammation (myocarditis of pericarditis) in young people had been reported after Pfizer and Moderna Covid-19 vaccination.

  • More than half were after the second dose.
  • Most of the injuries are in males under age 30.

Myocarditis and Other Cardiovascular Complications of the mRNA-Based COVID-19 Vaccines [Pfizer-BioNTech, Moderna] in a number of patients are described in a scientific article:

  • Two patients with clinically suspected myocarditis
  • One patient with stress cardiomyopathy 
  • Two patients with pericarditis 

According to the research: 

  • The two patients with clinically suspected myocarditis were otherwise healthy young men who presented with acute substernal chest pressure and/or dyspnea after receiving the second dose of the vaccine and were found to have diffuse ST elevations on electrocardiogram (ECG), elevated cardiac biomarkers and inflammatory markers, and mildly reduced left ventricular (LV) function on echocardiography. Both patients met the modified Lake Louise Criteria for acute myocarditis by cardiac magnetic resonance imaging. 
  • A case of stress cardiomyopathy occurred in a 60-year-old woman with known coronary artery disease (CAD) and previously normal LV function, who presented with new exertional symptoms, ECG changes, and apical akinesis following the second dose of the vaccine. 
  • The two patients with pericarditis who presented with chest pain, elevated inflammatory markers, and pericardial effusions after receiving the vaccine.

The Johnson and Johnson Covid-19 vaccine was temporarily removed from the market in the U.S. on April 16, 2021 while health officials studied reports of blood clot injuries. Among them was an 18-year old teen named Emma Burkey, who got sick about a week after the Johnson and Johnson Covid-19 vaccine and ended up having three brain surgeries related to blood clots and seizures.

The Johnson and Johnson vaccine was allowed back on the market April 27, 2021 with new warnings about the disorder.

An editorial published in the Journal of the American Medical Association recommended women under age 50 avoid the Johnson and Johnson Covid-19 vaccine due to concerns about blood clots. The recommendation discussed 12 case reports of a blood disorder known as cerebral venous sinus thrombosis (CVST) with thrombocytopenia following the Johnson and Johnson vaccine.

An otherwise healthy South Florida doctor, Gregory Michael, died of a brain hemorrhage 16 days after he got Pfizer’s Covid-19 vaccine. Authorities concluded he died of a blood disorder called “immune thrombocytopenia” (ITP) that can prevent blood from clotting and cause internal bleeding. His wife said a blood test showed the level of his platelets to be at “zero.” She said before the shot, Dr. Michael had “absolutely no medical issues” and no underlying conditions. However, authorities later categorized his death as “natural.”

Several clusters of elderly patients in U.S. nursing homes died after Pfizer or Moderna Covid-19 vaccine. In one group, a number of the patients who died tested positive for Covid-19 after vaccination.

CDC falsely claimed that studies showed Covid-19 vaccines are effective for those who already had Covid-19. In fact, studies showed the opposite.

Anonymous sources claimed that up to 60 million doses of the Johnson and Johnson vaccine had to be thrown out. But the FDA issued a news release saying that two batches from the Baltimore plant were safe to use. The FDA said “several other batches are not suitable for use, but additional batches are still under review.”

According to Epoch Times, in June 2021 nearly 4,000 fully vaccinated people in Massachusetts tested positive for Covid-19. On April 30, “the CDC reported that some 10,626 breakthrough cases were reported in 46 states and territories.” Breakthrough cases are where fully vaccinated people still end up infected with Covid-19.

Scientists hoped that Covid-19 vaccines would be effective in variants of Covid-19, which are mutations that occur naturally with viruses and were always expected with Covid-19. However, the vaccine effectiveness against variants may be limited. CDC and vaccine makers are studying the medical landscape to find out more.

Other states, such as Maine, are noting Covid-19 deaths occurring in fully vaccinated people.

Additional reading and studies

Zuckerman DM. Emergency Use Authorizations (EUAs) Versus FDA Approval: Implications for COVID-19 and Public Health. Am J Public Health [Internet]. 2021 Jun;111(6):1065–9. Available from: http://dx.doi.org/10.2105/AJPH.2021.306273 

Food and Drug Administration. Development and Licensure of Vaccines to Prevent COVID-19: Guidance for Industry [Internet]. 2020 [cited 2020 Oct 6]. Available from: https://www.fda.gov/media/139638/download 

Food and Drug Administration. FDA Briefing Document. Janssen Ad26.COV2.S Vaccine for the Prevention of COVID-19 [Internet]. 2021 [cited 2021 May 28]. Available from: https://www.fda.gov/media/146217/download 

CDC. Risk for COVID-19 infection, hospitalization, and death by age group [Internet]. 2021 [cited 2021 May 28]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/covid- data/investigations-discovery/hospitalization-death-by-age.html 

CDC. COVID-19 Pandemic Planning Scenarios [Internet]. 2021 [cited 2021 May 28]. Available from:
https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios.html 

CDC. Estimated disease burden of COVID-19 [Internet]. 2021 [cited 2021 May 28]. Available from:
https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/burden.html 

Dan JM, Mateus J, Kato Y, Hastie KM, Yu ED, Faliti CE, et al. Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science [Internet]. 2021 Feb 5;371(6529). Available from: http://dx.doi.org/10.1126/science.abf4063 

Turner JS, Kim W, Kalaidina E, Goss CW, Rauseo AM, Schmitz AJ, et al. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature [Internet]. 2021 May 24; Available from: http://dx.doi.org/10.1038/s41586-021-03647-4 

Breton G, Mendoza P, Hagglof T, Oliveira TY, Schaefer-Babajew D, Gaebler C, et al. Persistent Cellular Immunity to SARS-CoV-2 Infection. bioRxiv [Internet]. 2020 Dec 9; Available from: http://dx.doi.org/10.1101/2020.12.08.416636 

Hall VJ, Foulkes S, Charlett A, Atti A, Monk EJM, Simmons R, et al. SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN). Lancet [Internet]. 2021 Apr 17;397(10283):1459–69. Available from: http://dx.doi.org/10.1016/S0140-6736(21)00675-9 

Krammer F, Srivastava K, Simon V, the PARIS team. Robust spike antibody responses and increased reactogenicity in seropositive individuals after a single dose of SARS-CoV-2 mRNA vaccine [Internet]. bioRxiv. medRxiv; 2021. Available from: http://medrxiv.org/lookup/doi/10.1101/2021.01.29.21250653 

Samanovic MI, Cornelius AR, Wilson JP, Karmacharya T, Gray-Gaillard SL, Allen JR, et al. Poor antigen-specific responses to the second BNT162b2 mRNA vaccine dose in SARS-CoV-2-experienced individuals. medRxiv [Internet]. 2021 Feb 9; Available from: http://dx.doi.org/10.1101/2021.02.07.21251311 

Camara C, Lozano-Ojalvo D, Lopez-Granados E, Paz-Artal E, Pion M, Correa-Rocha R, et al. Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naïve and COVID-19 recovered individuals [Internet]. bioRxiv. 2021 [cited 2021 May 28]. p. 2021.03.22.436441. Available from: https://www.biorxiv.org/content/10.1101/2021.03.22.436441v1

Levi R, Azzolini E, Pozzi C, Ubaldi L, Lagioia M, Mantovani A, et al. A cautionary note on recall vaccination in ex-COVID-19 subjects [Internet]. bioRxiv. medRxiv; 2021. Available from: http://medrxiv.org/lookup/doi/10.1101/2021.02.01.21250923 

Ogata AF, Cheng C-A, Desjardins M, Senussi Y, Sherman AC, Powell M, et al. Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. Clin Infect Dis [Internet]. 2021 May 20; Available from: http://dx.doi.org/10.1093/cid/ciab465 

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Ungekrzte

"Enlightenment is man's emergence from his self-imposed immaturity ... the inability to use one's own understanding without another's guidance. This immaturity is self-imposed if its cause lies not in lack of understanding but in indecision and lack of courage to use one's own mind without another's guidance. Dare to know! (Sapere aude.) "Have the courage to use your own understanding," is therefore the motto of the [European] Enlightenment. "Laziness and cowardice are the reasons why such a large part of mankind gladly remain minors all their lives, long after nature has freed them from external guidance. They are the reasons why it is so easy for others to set themselves up as guardians. It is so comfortable to be a minor. If I have a book that thinks for me, a pastor who acts as my conscience, a physician who prescribes my diet [or vaccine], and so on--then I have no need to exert myself. I have no need to think, if only I can pay; others will take care of that disagreeable business for me. Those guardians who have kindly taken supervision upon themselves see to it that the overwhelming majority of mankind ... should consider the step to maturity, not only as hard, but as extremely dangerous. First, these guardians make their domestic cattle stupid and carefully prevent the docile creatures from taking a single step without the leading-strings to which they have fastened them. Then they show them the danger that would threaten them if they should try to walk by themselves. Now this danger is really not very great; after stumbling a few times they would, at last, learn to walk. However, examples of such failures intimidate and generally discourage all further attempts. "Thus it is very difficult for the individual to work himself out of the immaturity which has become almost second nature to him. He has even grown to like it, and is at first really incapable of using his own understanding because he has never been permitted to try it. Dogmas and formulas [e.g., Leftist ideology, identity politics] these mechanical tools designed for reasonable use--or rather abuse--of his natural gifts, are the fetters of an everlasting immaturity. The man who casts them off would make an uncertain leap over the narrowest ditch, because he is not used to such free movement. That is why there are only a few men who walk firmly, and who have emerged from immaturity by cultivating their own minds." - Kant, "An Answer to the Question: What is Enlightenment"

One thought on ““Why so many vaccinated people are getting sick: Antibody Dependent Enhancement (ADE)”; and “Exclusive Summary: Covid-19 Vaccine Concerns””

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